Acyline [170157-13-8]

TargetMol Chemicals

Acyline [170157-13-8]

114

Research Use Only

Acyline

C80H102ClN15O14

1533.21

Acyline is a novel GnRH antagonist found in animal studies to be a potent suppressor of circulating gonadotropin and testosterone (T) levels. Acyline inhibits basal and GnRH-stimulated serum testosterone concentrations in male dogs. Acyline prevented ovulation, but did not affect ovarian follicular development or gestational corpora lutea in the domestic cat. A single dose of the potent gonadotropin-releasing hormone antagonist acyline suppresses gonadotropins and testosterone for 2 weeks in healthy young men.

3 years

C([C@@H](NC([C@@H](NC([C@@H](CC1=CC=C(NC(C)=O)C=C1)NC([C@H](CC2=CC=C(NC(C)=O)C=C2)NC([C@@H](NC([C@@H](CC=3C=CC=NC3)NC([C@@H](CC4=CC=C(Cl)C=C4)NC([C@@H](CC5=CC6=C(C=C5)C=CC=C6)NC(C)=O)=O)=O)=O)CO)=O)=O)=O)CC(C)C)=O)CCCCNC(C)C)(=O)N7[C@H](C(N[C@@H](C(N)=O)C)=O)CCC7

-20°C

12352200