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Adaptaquin [385786-48-1]

M6406
AbMole BioScience
CAS Number385786-48-1
Product group Chemicals
Estimated Puritymore then99.0%
Molecular Weight377.82
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Overview

  • Supplier
    AbMole BioScience
  • Product Name
    Adaptaquin [385786-48-1]
  • Delivery Days Customer
    7
  • CAS Number
    385786-48-1
  • Certification
    Research Use Only
  • Estimated Purity
    more then99.0%
  • Molecular Formula
    C21H16ClN3O2
  • Molecular Weight
    377.82
  • Scientific Description
    Adaptaquin is a hIF-prolyl hydroxylase-2 (PHD2) inhibitor. Adaptaquin blocks glutamate induced ROS production in HT-22 cells, independent of MnSOD. Adaptaquin exhibits neuroprotective effects and enhances functional recovery in rodent intracerebral hemorrhage models, via inhibition of ATF4 dependent genes. Brain penetrant. Also antioxidant.
  • SMILES
    OC1=C(NC(C2=CC=C(Cl)C=C2)C3=C(O)C4=C(C=CC=N4)C=C3)N=CC=C1
  • Storage Instruction
    -20°C
  • UNSPSC
    12161500

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References
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