Adavosertib (MK-1775)
M2143
CAS Number955365-80-7
Product group Chemicals
Estimated Purity0.9989
Molecular Weight500.61
Overview
- SupplierAbMole BioScience
- Product NameAdavosertib（MK-1775）
- Delivery Days Customer9
- CAS Number955365-80-7
- Category SupplierChemical
- CertificationResearch Use Only
- Estimated Purity0.9989
- Molecular FormulaC27H32N8O2
- Molecular Weight500.61
- Scientific DescriptionAdavosertib (AZD1775, MK-1775) is a small pyrazolacil derivative, an effective ATP competitive specific inhibitor of WEE1 kinase, with IC50 of 5.2 nM. It can inhibit G2 phase DNA damage test sites.
- SMILESCN1CCN(CC1)C2=CC=C(NC3=NC4=C(C=N3)C(=O)N(CC=C)N4C5=NC(=CC=C5)C(C)(C)O)C=C2
- UNSPSC12352200