Adenosine-5-O-(3-thiotriphosphate) sodium [88453-52-5]

TargetMol Chemicals

Adenosine-5-O-(3-thiotriphosphate) sodium [88453-52-5]

44

Chemical

Research Use Only

Adenosine-5'-O-(3-thiotriphosphate) sodium

C10H12N5O12P3S.4Na

611.18

Adenosine-5-O-(3-thiotriphosphate) (ATPgammaS), an agonist of the purinergic P2Y11 receptor, prompts inositol phosphate accumulation in CHO-K1 cells harboring the human or canine P2Y11 receptor with EC50 values of 1.2 and 19.3 microM, respectively. At a concentration of 10 microM, ATPgammaS mitigates Junin virus-induced mRNA boosts pertaining to bone morphogenetic protein 6 (BMP6) and diminishes particle forming units (PFUs) in infected primary rat osteoblasts. Furthermore, when applied at 25 microM, it triggers insulin secretion in MIN6 pancreatic beta-cells.

3 years

O[C@@H]1[C@@H](COP(OP(OP([O-])([S-])=O)([O-])=O)([O-])=O)O[C@@H](N2C3=NC=NC(N)=C3N=C2)[C@@H]1O.[Na+].[Na+].[Na+].[Na+]

-20°C

12352200