Adrogolide (hydrochloride) [166591-11-3]

MedChem Express

Adrogolide (hydrochloride) [166591-11-3]

5

166591-11-3

Research Use Only

99.14

C22H26ClNO4S

435.96

Adrogolide hydrochloride (ABT-431 hydrochloride) is a chemically stable prodrug that can convert to the dopamine D1 receptor agonist A-86929. Adrogolide hydrochloride ameliorates the MPTP (HY-15608)-induced Parkinsons Disease in marmoset model, reduces the dyskinesias tendency. Adrogolide hydrochloride reverses Risperidone (HY-11018)-induced cognitive deficits in monkey[1].

CCCC1=CC2=C(CN[C@@]3(CCC4=CC(OC(C)=O)=C(C=C4[C@@]23[H])OC(C)=O)[H])S1.[H]Cl

RT

12352200