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ADTL-SA1215 [782387-91-1]

ADTL-SA1215 [782387-91-1]

T40891
TargetMol Chemicals
CAS Number782387-91-1
DownloadMSDS
Product group Chemicals
Estimated Purity99.23%
Molecular Weight657.32
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Overview

  • Supplier
    TargetMol Chemicals
  • Product Name
    ADTL-SA1215 [782387-91-1]
  • Delivery Days Customer
    14
  • CAS Number
    782387-91-1
  • Category Supplier
    Chemical
  • Certification
    Research Use Only
  • Chemical Name
    ADTL-SA1215
  • Estimated Purity
    99.23%
  • Molecular Formula
    C26H29I2NO3
  • Molecular Weight
    657.32
  • Scientific Description
    ADTL-SA1215 is a selective SIRT3 activator with SIRT3 deacetylase activity that inhibits the proliferation and migration of human breast cancer MDA-MB-231 cells through the SIRT3-driven autophagy/mitochondrial autophagy signaling pathway, and can be used in the study of triple negative breast cancer.
  • Shelf life instruction
    3 years
  • SMILES
    CCCCc1oc2ccccc2c1C(=O)c1cc(I)c(OCCCN2CCCC2)c(I)c1
  • Storage Instruction
    -20°C
  • UNSPSC
    12352200

References

  • Structure-Guided Design of a Small-Molecule Activator of Sirtuin-3 that Modulates Autophagy in Triple Negative Breast Cancer. Zhang J et al., 2021 Oct 14, J Med Chem
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