ADX-47273

MedChem Express

ADX-47273 [851881-60-2]

10

851881-60-2

Research Use Only

99.94

C20H17F2N3O2

369.36

ADX-47273 is a potent, selective and brain-penetrant mGluR5 positive allosteric modulator (PAM), with an EC50 of 0.17 microM for potentiation of glutamate (50 nM) response. ADX-47273 has antipsychotic and procognitive activities[1][2].

O=C(C1=CC=C(F)C=C1)N2C[C@@H](C3=NC(C4=CC=C(F)C=C4)=NO3)CCC2

-20°C,2°C to 8°C

12352200