AF-DX 384 [118290-26-9]

MedChem Express

AF-DX 384 [118290-26-9]

10

118290-26-9

Research Use Only

98.0

C27H38N6O2

478.63

AF-DX 384 is a selective antagonist of M2 and M4 muscarinic acetylcholine receptors (Kis=6.03 and 10 nM, respectively)[1]. AF-DX 384 reverses deficits in novel object recognition and passive avoidance in aged rats, as well as in young rats with impairments induced by scopolamine[2].

O=C1NC2=CC=CN=C2N(C3=C1C=CC=C3)C(NCCN4CCCCC4CN(CCC)CCC)=O

-20°C

12352200