AF488 Anti-Mouse CD161/NK1.1 Antibody
RD20045F
ApplicationsFlow Cytometry
Product group Antibodies
ReactivityMouse
TargetKlrb1c
Overview
- SupplierReddot Biotech
- Product NameAF488 Anti-Mouse CD161/NK1.1 Antibody
- Delivery Days Customer5
- ApplicationsFlow Cytometry
- CertificationResearch Use Only
- ClonalityMonoclonal
- Clone IDPK136
- Concentration0.5 mg/ml
- ConjugateAlexaFluor 488
- Gene ID17059
- Target nameKlrb1c
- Target descriptionkiller cell lectin-like receptor subfamily B member 1C
- Target synonymsAI462337; CD161; CD161 antigen-like family member C; killer cell lectin-like receptor subfamily A member 1C; killer cell lectin-like receptor subfamily B member 1C; Klrb1b; Ly5; Ly-5; Ly55; Ly55c; ly-55c; Ly59; Ly-59; lymphocyte antigen 55 complex, locus C; lymphocyte antigen 55c; lymphocyte antigen 59; natural killer cell receptor protein NKR-P1C; natural killer cell receptor-P1; natural killer cell surface protein P1-40; natural killer cell-associated antigen 1; Nk; NK-; Nk1; Nk-1; Nk1.; NK-1.; NK1.1; Nk1.2; Nk-1.2; NKR; NKR-; Nkrp; NKRP1; NK-RP1; NKR-P1 40; NKR-P1.9; NKRP140; Nkrp1b; NKR-P1B; Nkrp1c
- HostMouse
- IsotypeIgG2a
- Scientific DescriptionNK-1.1 surface antigen, also known as CD161b/CD161c and Ly-55, is encoded by the NKR-P1B/NKR-P1C gene. It is expressed on NK cells and NK-T cells in some mouse strains, including C57BL/6, FVB/N, and NZB, but not AKR, BALB/c, CBA/J, C3H, DBA/1, DBA/2, NOD, SJL, and 129. Expression of NKR-P1C antigen has been correlated with lysis of tumor cells in vitro and rejection of bone marrow allografts in vivo. NK-1.1 has also been shown to play a role in NK cell activation, IFN-Oe≥ production, and cytotoxic granule release. NK-1.1 and DX5 are commonly used as mouse NK cell markers.
- ReactivityMouse
- Storage Instruction2°C to 8°C
- UNSPSC12352203