Bio-Connect

AF488 Anti-Mouse CD161/NK1.1 Antibody

Research Use Only
RD20045F
Reddot Biotech
ApplicationsFlow Cytometry
Product group Antibodies
ReactivityMouse
TargetKlrb1c
Price on request
Packing Size
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Overview

  • Supplier
    Reddot Biotech
  • Product Name
    AF488 Anti-Mouse CD161/NK1.1 Antibody
  • Delivery Days Customer
    5
  • Applications
    Flow Cytometry
  • Certification
    Research Use Only
  • Clonality
    Monoclonal
  • Clone ID
    PK136
  • Concentration
    0.5 mg/ml
  • Conjugate
    AlexaFluor 488
  • Gene ID17059
  • Target name
    Klrb1c
  • Target description
    killer cell lectin-like receptor subfamily B member 1C
  • Target synonyms
    AI462337; CD161; CD161 antigen-like family member C; killer cell lectin-like receptor subfamily A member 1C; killer cell lectin-like receptor subfamily B member 1C; Klrb1b; Ly5; Ly-5; Ly55; Ly55c; ly-55c; Ly59; Ly-59; lymphocyte antigen 55 complex, locus C; lymphocyte antigen 55c; lymphocyte antigen 59; natural killer cell receptor protein NKR-P1C; natural killer cell receptor-P1; natural killer cell surface protein P1-40; natural killer cell-associated antigen 1; Nk; NK-; Nk1; Nk-1; Nk1.; NK-1.; NK1.1; Nk1.2; Nk-1.2; NKR; NKR-; Nkrp; NKRP1; NK-RP1; NKR-P1 40; NKR-P1.9; NKRP140; Nkrp1b; NKR-P1B; Nkrp1c
  • Host
    Mouse
  • Isotype
    IgG2a
  • Scientific Description
    NK-1.1 surface antigen, also known as CD161b/CD161c and Ly-55, is encoded by the NKR-P1B/NKR-P1C gene. It is expressed on NK cells and NK-T cells in some mouse strains, including C57BL/6, FVB/N, and NZB, but not AKR, BALB/c, CBA/J, C3H, DBA/1, DBA/2, NOD, SJL, and 129. Expression of NKR-P1C antigen has been correlated with lysis of tumor cells in vitro and rejection of bone marrow allografts in vivo. NK-1.1 has also been shown to play a role in NK cell activation, IFN-Oe≥ production, and cytotoxic granule release. NK-1.1 and DX5 are commonly used as mouse NK cell markers.
  • Reactivity
    Mouse
  • Storage Instruction
    2°C to 8°C
  • UNSPSC
    12352203