NK1.1 antibody [PK136]
GTX01478
ApplicationsFlow Cytometry, ImmunoPrecipitation, ImmunoHistoChemistry, ImmunoHistoChemistry Frozen, ImmunoHistoChemistry Paraffin, Neutralisation/Blocking, Other Application
Product group Antibodies
TargetKlrb1c
Overview
- SupplierGeneTex
- Product NameNK1.1 antibody [PK136]
- Delivery Days Customer9
- Application Supplier Note*Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.
- ApplicationsFlow Cytometry, ImmunoPrecipitation, ImmunoHistoChemistry, ImmunoHistoChemistry Frozen, ImmunoHistoChemistry Paraffin, Neutralisation/Blocking, Other Application
- CertificationResearch Use Only
- ClonalityMonoclonal
- Clone IDPK136
- Concentration0.5 mg/ml
- ConjugateUnconjugated
- Gene ID17059
- Target nameKlrb1c
- Target descriptionkiller cell lectin-like receptor subfamily B member 1C
- Target synonymsCD161, Klrb1b, Ly-59, Ly55c, Ly59, NK-RP1, NK1.1, NKR-P1.9, NKRP1, NKRP140, Nk-1, Nk-1.2, Nk1, Nk1.2, Nkrp1b, Nkrp1c, ly-55c, killer cell lectin-like receptor subfamily B member 1C, CD161 antigen-like family member C, NKR-P1 40, NKR-P1B, killer cell lectin-like receptor subfamily A member 1C, lymphocyte antigen 55 complex, locus C, lymphocyte antigen 55c, lymphocyte antigen 59, natural killer cell receptor protein NKR-P1C, natural killer cell receptor-P1, natural killer cell surface protein P1-40, natural killer cell-associated antigen 1
- HostMouse
- IsotypeIgG2a
- Protein IDP27814
- Protein NameKiller cell lectin-like receptor subfamily B member 1C
- Storage Instruction2°C to 8°C
- UNSPSC12352203
References
- Lin X, Zeng T, Xiong J, et al. Combined α-programmed death-1 monoclonal antibody blockade and fractionated radiation therapy reduces tumor growth in mouse EL4 lymphoma. Cancer Biol Ther. 2019,20(5):666-679. doi: 10.1080/15384047.2018.1550569Read this paper
- Mukherjee S, Fried A, Hussaini R, et al. Phytosomal curcumin causes natural killer cell-dependent repolarization of glioblastoma (GBM) tumor-associated microglia/macrophages and elimination of GBM and GBM stem cells. J Exp Clin Cancer Res. 2018,37(1):168. doi: 10.1186/s13046-018-0792-5Read this paper
- Krebs DL, Chehal MK, Sio A, et al. Lyn-dependent signaling regulates the innate immune response by controlling dendritic cell activation of NK cells. J Immunol. 2012,188(10):5094-105. doi: 10.4049/jimmunol.1103395Read this paper
- Diamond MS, Kinder M, Matsushita H, et al. Type I interferon is selectively required by dendritic cells for immune rejection of tumors. J Exp Med. 2011,208(10):1989-2003. doi: 10.1084/jem.20101158Read this paper
- Lubinski JM, Lazear HM, Awasthi S, et al. The herpes simplex virus 1 IgG fc receptor blocks antibody-mediated complement activation and antibody-dependent cellular cytotoxicity in vivo. J Virol. 2011,85(7):3239-49. doi: 10.1128/JVI.02509-10Read this paper
- Awasthi A, Samarakoon A, Chu H, et al. Rap1b facilitates NK cell functions via IQGAP1-mediated signalosomes. J Exp Med. 2010,207(9):1923-38. doi: 10.1084/jem.20100040Read this paper
- Coudert JD, Scarpellino L, Gros F, et al. Sustained NKG2D engagement induces cross-tolerance of multiple distinct NK cell activation pathways. Blood. 2008,111(7):3571-8. doi: 10.1182/blood-2007-07-100057Read this paper
- Ljutic B, Carlyle JR, Filipp D, et al. Functional requirements for signaling through the stimulatory and inhibitory mouse NKR-P1 (CD161) NK cell receptors. J Immunol. 2005,174(8):4789-96.Read this paper
- Kanwar JR, Shen WP, Kanwar RK, et al. Effects of survivin antagonists on growth of established tumors and B7-1 immunogene therapy. J Natl Cancer Inst. 2001,93(20):1541-52.Read this paper

![FACS analysis of mouse C57Bl/6 splenocytes using GTX01478-02 NK1.1 antibody [PK136] (Biotin). Right panel : co-stained with NK1.1 antibody [PK136] (Biotin) and Mouse CD3e antibody (APC) Left panel : co-stained with isotype control and Mouse CD3e antibody (APC) antibody amount : 0.25 microg (5 microl)](https://www.genetex.com/upload/website/prouct_img/normal/GTX01478-02/GTX01478-02_20200428_FACS62_w_23053121_471.webp)
![FACS analysis of mouse C57Bl/6 splenocytes using GTX01478-06 NK1.1 antibody [PK136] (FITC). Solid lone : primary antibody Dashed line : isotype control antibody amount : 0.5 microg (5 microl)](https://www.genetex.com/upload/website/prouct_img/normal/GTX01478-06/GTX01478-06_20200428_FACS87_w_23053121_991.webp)
![FACS analysis of mouse C57Bl/6 splenocytes using GTX01478-07 NK1.1 antibody [PK136] (APC). Right panel : co-stained with NK1.1 antibody [PK136] (APC) and Mouse CD3e antibody (FITC) Left panel : co-stained with isotype control and Mouse CD3e antibody (FITC) antibody amount : 0.125 microg (5 microl)](https://www.genetex.com/upload/website/prouct_img/normal/GTX01478-07/GTX01478-07_20200428_FACS31_w_23053121_786.webp)
![FACS analysis of mouse C57Bl/6 splenocytes using GTX01478-08 NK1.1 antibody [PK136] (PE). Right panel : co-stained with NK1.1 antibody [PK136] (PE) and Mouse CD3e antibody (APC) Left panel : co-stained with isotype control and Mouse CD3e antibody (APC) antibody amount : 0.5 microg (5 microl)](https://www.genetex.com/upload/website/prouct_img/normal/GTX01478-08/GTX01478-08_20200428_FACS125_w_23053121_372.webp)
![FACS analysis of mouse C57Bl/6 splenocytes using GTX01478-10 NK1.1 antibody [PK136] (PE-Cy7). Right panel : co-stained with NK1.1 antibody [PK136] (PE-Cy7) and Mouse CD3e antibody (APC) Left panel : co-stained with isotype control and Mouse CD3e antibody (APC) antibody amount : 0.5 microg (5 microl)](https://www.genetex.com/upload/website/prouct_img/normal/GTX01478-10/GTX01478-10_20200428_FACS149_w_23053121_592.webp)
![FACS analysis of mouse C57Bl/6 splenocytes using GTX01478-11 NK1.1 antibody [PK136] (PerCP-Cy5.5). Right panel : co-stained with NK1.1 antibody [PK136] (PerCP-Cy5.5) and Mouse CD3e antibody (FITC) Left panel : co-stained with isotype control and Mouse CD3e antibody (FITC) antibody amount : 0.25 microg (5 microl)](https://www.genetex.com/upload/website/prouct_img/normal/GTX01478-11/GTX01478-11_20200428_FACS169_w_23053121_468.webp)
