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NK1.1 antibody [PK136]

GTX01478
GeneTex
ApplicationsFlow Cytometry, ImmunoPrecipitation, ImmunoHistoChemistry, ImmunoHistoChemistry Frozen, ImmunoHistoChemistry Paraffin, Neutralisation/Blocking, Other Application
Product group Antibodies
TargetKlrb1c
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Overview

  • Supplier
    GeneTex
  • Product Name
    NK1.1 antibody [PK136]
  • Delivery Days Customer
    9
  • Application Supplier Note
    *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.
  • Applications
    Flow Cytometry, ImmunoPrecipitation, ImmunoHistoChemistry, ImmunoHistoChemistry Frozen, ImmunoHistoChemistry Paraffin, Neutralisation/Blocking, Other Application
  • Certification
    Research Use Only
  • Clonality
    Monoclonal
  • Clone ID
    PK136
  • Concentration
    0.5 mg/ml
  • Conjugate
    Unconjugated
  • Gene ID17059
  • Target name
    Klrb1c
  • Target description
    killer cell lectin-like receptor subfamily B member 1C
  • Target synonyms
    CD161, Klrb1b, Ly-59, Ly55c, Ly59, NK-RP1, NK1.1, NKR-P1.9, NKRP1, NKRP140, Nk-1, Nk-1.2, Nk1, Nk1.2, Nkrp1b, Nkrp1c, ly-55c, killer cell lectin-like receptor subfamily B member 1C, CD161 antigen-like family member C, NKR-P1 40, NKR-P1B, killer cell lectin-like receptor subfamily A member 1C, lymphocyte antigen 55 complex, locus C, lymphocyte antigen 55c, lymphocyte antigen 59, natural killer cell receptor protein NKR-P1C, natural killer cell receptor-P1, natural killer cell surface protein P1-40, natural killer cell-associated antigen 1
  • Host
    Mouse
  • Isotype
    IgG2a
  • Protein IDP27814
  • Protein Name
    Killer cell lectin-like receptor subfamily B member 1C
  • Storage Instruction
    2°C to 8°C
  • UNSPSC
    12352203

References

  • Lin X, Zeng T, Xiong J, et al. Combined α-programmed death-1 monoclonal antibody blockade and fractionated radiation therapy reduces tumor growth in mouse EL4 lymphoma. Cancer Biol Ther. 2019,20(5):666-679. doi: 10.1080/15384047.2018.1550569
    Read this paper
  • Mukherjee S, Fried A, Hussaini R, et al. Phytosomal curcumin causes natural killer cell-dependent repolarization of glioblastoma (GBM) tumor-associated microglia/macrophages and elimination of GBM and GBM stem cells. J Exp Clin Cancer Res. 2018,37(1):168. doi: 10.1186/s13046-018-0792-5
    Read this paper
  • Krebs DL, Chehal MK, Sio A, et al. Lyn-dependent signaling regulates the innate immune response by controlling dendritic cell activation of NK cells. J Immunol. 2012,188(10):5094-105. doi: 10.4049/jimmunol.1103395
    Read this paper
  • Diamond MS, Kinder M, Matsushita H, et al. Type I interferon is selectively required by dendritic cells for immune rejection of tumors. J Exp Med. 2011,208(10):1989-2003. doi: 10.1084/jem.20101158
    Read this paper
  • Lubinski JM, Lazear HM, Awasthi S, et al. The herpes simplex virus 1 IgG fc receptor blocks antibody-mediated complement activation and antibody-dependent cellular cytotoxicity in vivo. J Virol. 2011,85(7):3239-49. doi: 10.1128/JVI.02509-10
    Read this paper
  • Awasthi A, Samarakoon A, Chu H, et al. Rap1b facilitates NK cell functions via IQGAP1-mediated signalosomes. J Exp Med. 2010,207(9):1923-38. doi: 10.1084/jem.20100040
    Read this paper
  • Coudert JD, Scarpellino L, Gros F, et al. Sustained NKG2D engagement induces cross-tolerance of multiple distinct NK cell activation pathways. Blood. 2008,111(7):3571-8. doi: 10.1182/blood-2007-07-100057
    Read this paper
  • Ljutic B, Carlyle JR, Filipp D, et al. Functional requirements for signaling through the stimulatory and inhibitory mouse NKR-P1 (CD161) NK cell receptors. J Immunol. 2005,174(8):4789-96.
    Read this paper
  • Kanwar JR, Shen WP, Kanwar RK, et al. Effects of survivin antagonists on growth of established tumors and B7-1 immunogene therapy. J Natl Cancer Inst. 2001,93(20):1541-52.
    Read this paper