Afatinib (dimaleate) (Standard)
HY-10261AR
Product group Assays
Overview
- SupplierMedChem Express
- Product NameAfatinib (dimaleate) (Standard) [850140-73-7]
- Delivery Days Customer5
- CertificationResearch Use Only
- Scientific DescriptionAfatinib (dimaleate) (Standard) is the analytical standard of Afatinib (dimaleate). This product is intended for research and analytical applications. Afatinib (BIBW 2992) dimaleate is an orally active, potent and irreversible dual specificity inhibitor of ErbB family (EGFR and HER2), with IC50 values of 0.5 nM, 0.4 nM, 10 nM and 14 nM for EGFRwt, EGFRL858R, EGFRL858R/T790M and HER2, respectively. Afatinib dimaleate can be used for the research of esophageal squamous cell carcinoma (ESCC), non-small cell lung cancer (NSCLC) and gastric cancer [1] [2] [3] [4] .
- UNSPSC41116135