AF/LE Purified Anti-Mouse CD132 Antibody

Reddot Biotech

AF/LE Purified Anti-Mouse CD132 Antibody

5

Flow Cytometry

Research Use Only

Monoclonal

0.5 mg/ml

Unconjugated

Il2rg

interleukin 2 receptor, gamma chain

[g]c; CD132; common gamma chain; cytokine receptor common subunit gamma; gamm; gamma C receptor; gamma(; gamma(c); gc; IL-2 receptor subunit gamma; IL-2R subunit gamma; interleukin-2 receptor subunit gamma; p64

Rat

IgG2b

CD132 is a 64-70 kD type I transmembrane glycoprotein of the Ig superfamily, and is also known as common Oe≥ chain (Oe≥c) or IL-2 receptor Oe≥ subunit. It is expressed broadly on T- and B-lymphocytes, NK cells, monocytes, and granulocytes. CD132 is an essential component of cytokine receptors for IL-2, IL-4, IL-7, IL-9, IL-15, and IL-21. Ligand binding induces tyrosine phosphorylation and initiates signaling through a JAK/STAT pathway. CD132 mutation results in X-linked severe combined immune deficiency (XSCID).

2°C to 8°C

12352203