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AFN-1252

HY-16911
MedChem Express
CAS Number620175-39-5
DownloadMSDS
Product group Chemicals
Estimated Purity99.49
Molecular Weight375.42
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Overview

  • Supplier
    MedChem Express
  • Product Name
    AFN-1252 [620175-39-5]
  • Delivery Days Customer
    10
  • CAS Number
    620175-39-5
  • Certification
    Research Use Only
  • Estimated Purity
    99.49
  • Molecular Formula
    C22H21N3O3
  • Molecular Weight
    375.42
  • Scientific Description
    AFN-1252 is an orally active and selective inhibitor of FabI , an essential enzyme in fatty acid biosynthesis in Staphylococcus spp. AFN-1252 exhibits exquisite and highly selective activity against Staphylococcus spp. AFN-1252 exhibits typical MIC 90 values of <=0.015 microg/ml against diverse clinical isolates of S. aureus . AFN-1252 is efficacious in a mouse model of septicemia providing 100% protection from an otherwise lethal peritoneal infection of S. aureus Smith [1] [2] .
  • SMILES
    O=C(N(C)CC1=C(C)C2=CC=CC=C2O1)/C=C/C(C=C3CC4)=CNC3=NC4=O
  • Storage Instruction
    -20°C,2°C to 8°C
  • UNSPSC
    12352200