Afoxolaner [1093861-60-9]

MedChem Express

Afoxolaner [1093861-60-9]

10

1093861-60-9

Research Use Only

99.95

C26H17ClF9N3O3

625.87

Afoxolaner is an orally active isoxazoline insecticide/acaricide against Ixodes scapularis in dogs. Afoxolaner acts on the insect gamma-aminobutyric acid receptor (GABA) and glutamate receptors, inhibiting GABA & glutamate-regulated uptake of chloride ions, resulting in excess neuronal stimulation and death of the arthropod[1][2].

O=C(C1=C2C=CC=CC2=C(C3=NOC(C(F)(F)F)(C4=CC(C(F)(F)F)=CC(Cl)=C4)C3)C=C1)NCC(NCC(F)(F)F)=O

-20°C,2°C to 8°C

12352200