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Afuresertib (hydrochloride)

HY-15727A
MedChem Express
CAS Number1047645-82-8
Product group Chemicals
Estimated Purity99.95
Molecular Weight463.78
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Overview

  • Supplier
    MedChem Express
  • Product Name
    Afuresertib (hydrochloride) [1047645-82-8]
  • Delivery Days Customer
    10
  • CAS Number
    1047645-82-8
  • Certification
    Research Use Only
  • Estimated Purity
    99.95
  • Molecular Formula
    C18H18Cl3FN4OS
  • Molecular Weight
    463.78
  • Scientific Description
    Afuresertib hydrochloride (GSK 2110183 hydrochloride) is an orally bioavailable, selective, ATP-competitive and potent pan-Akt kinase inhibitor with K i s of 0.08/2/2.6 nM for Akt1/Akt2/Akt3 respectively [1] [2] .
  • SMILES
    O=C(C1=CC(C2=C(Cl)C=NN2C)=C(Cl)S1)N[C@@H](CC3=CC=CC(F)=C3)CN.[H]Cl
  • Storage Instruction
    -20°C
  • UNSPSC
    12352200