Afuresertib

AbMole BioScience

Afuresertib

9

1047644-62-1

Chemical

Research Use Only

C18H17Cl2FN4OS

427.32

Afuresertib (GSK2110183; LAE002) is a potent, orally bioavailable Akt inhibitor with Ki of 0.08 nM, 2 nM, and 2.6 nM for Akt1, Akt2, and Akt3, respectively.

C[N]1N=CC(=C1C2=C(Cl)SC(=C2)C(=O)NC(CN)CC3=CC=CC(=C3)F)Cl

-20°C, protect from light, sealed

12352200