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AGK7 [304896-21-7]

AGK7 [304896-21-7]

T22026
TargetMol Chemicals
CAS Number304896-21-7
Product group Chemicals
Estimated Purity98.31%
Molecular Weight434.27
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Overview

  • Supplier
    TargetMol Chemicals
  • Product Name
    AGK7 [304896-21-7]
  • Delivery Days Customer
    9
  • CAS Number
    304896-21-7
  • Certification
    Research Use Only
  • Chemical Name
    AGK7
  • Estimated Purity
    98.31%
  • Molecular Formula
    C23H13Cl2N3O2
  • Molecular Weight
    434.27
  • Scientific Description
    AGK7 is an inactive control of AGK2, a selective SIRT2 inhibitor that selectively inhibits SIRT3 over SIRT1 and SIRT2 (IC50 = >5 microM, >50 microM and >50 microM for SIRT3, SIRT1, and SIRT2, respectively).
  • Shelf life instruction
    3 years
  • SMILES
    ClC1=CC=C(Cl)C(=C1)C1=CC=C(O1)\C=C(/C#N)C(=O)NC1=C2N=CC=CC2=CC=C1
  • Storage Instruction
    -20°C
  • UNSPSC
    12352200

References

  • Outeiro TF, Kontopoulos E, Altmann SM, et al. Sirtuin 2 inhibitors rescue alpha-synuclein-mediated toxicity in models of Parkinson's disease. Science. 2007,317(5837):516-9.
    Read this paper