AGN 192870 [166977-57-7]

MedChem Express

AGN 192870 [166977-57-7]

10

166977-57-7

Research Use Only

98.10

C27H22O2

378.46

AGN 192870 is a RAR neutral antagonist with Kds of 147, 33, and 42 nM for RARalpha, RARbeta, and RARgamma, respectively. AGN 192870 shows IC50s of 87 and 32 nM for RARalphaand RARgamma, respectively. AGN 192870 shows RARbeta partial agonism[1]. AGN 192870 is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.

O=C(C1=CC=C(C=C1)C#CC2=CC(C(C3=CC=CC=C3)=CCC4(C)C)=C4C=C2)O

-20°C,2°C to 8°C

12352200