AGN 192870

MedChem Express

AGN 192870 [166977-57-7]

10

166977-57-7

Research Use Only

98.10

C27H22O2

378.46

AGN 192870 is a RAR neutral antagonist with K d s of 147, 33, and 42 nM for RARalpha, RARbeta, and RARgamma, respectively. AGN 192870 shows IC 50 s of 87 and 32 nM for RARalphaand RARgamma, respectively. AGN 192870 shows RARbeta partial agonism [1] . AGN 192870 is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.

O=C(C1=CC=C(C=C1)C#CC2=CC(C(C3=CC=CC=C3)=CCC4(C)C)=C4C=C2)O

-20°C,2°C to 8°C

12352200