AH-1058 [228123-15-7]
HY-116500A
CAS Number228123-15-7
Product group Chemicals
Molecular Weight501.02
Overview
- SupplierMedChem Express
- Product NameAH-1058 [228123-15-7]
- Delivery Days Customer9
- CAS Number228123-15-7
- CertificationResearch Use Only
- Molecular FormulaC30H29ClN2O3
- Molecular Weight501.02
- Scientific DescriptionAH-1058 is a newly synthesized antiarrhythmic agent that exhibits significant antiarrhythmic activity by delaying premature ventricular complexes and ventricular fibrillation in experimental arrhythmia models. AH-1058 effectively inhibits both ventricular tachycardia and ventricular fibrillation in the reperfusion-induced arrhythmia model in rats. AH-1058 demonstrates potent calcium channel-blocking effects, suppressing L-type Ca2+ currents in isolated cardiomyocytes.
- SMILESO=[N+]([O-])C1=C(C=CC=C1/C=C/CN2CC/C(CC2)=C3C4=CC=CC=C4C=CC5=CC=CC=C/35)OC.Cl
- UNSPSC12352200