
WB analysis of human spleen lysate using GTX89216 AIRE (isoforms 1 + 2) antibody, Internal. Dilution : 0.3microg/ml Loading : 35microg protein in RIPA buffer
AIRE (isoforms 1 + 2) antibody, Internal
GTX89216
Overview
- SupplierGeneTex
- Product NameAIRE (isoforms 1 + 2) antibody, Internal
- Delivery Days Customer7
- Application Supplier NoteWB: 0.3-1microg/ml. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.
- ApplicationsWestern Blot
- CertificationResearch Use Only
- ClonalityPolyclonal
- Concentration0.50 mg/ml
- ConjugateUnconjugated
- Gene ID326
- Target nameAIRE
- Target descriptionautoimmune regulator
- Target synonymsAIRE1; APECED; APS1; APSI; autoimmune polyendocrinopathy candidiasis ectodermal dystrophy protein; autoimmune regulator; PGA1
- HostGoat
- IsotypeIgG
- Protein IDO43918
- Protein NameAutoimmune regulator
- Scientific DescriptionThis gene encodes a transcriptional regulator that forms nuclear bodies and interacts with the transcriptional coactivator CREB binding protein. The encoded protein plays an important role in immunity by regulating the expression of autoantigens and negative selection of autoreactive T-cells in the thymus. Mutations in this gene cause the rare autosomal-recessive systemic autoimmune disease termed autoimmune polyendocrinopathy with candidiasis and ectodermal dystrophy (APECED). [provided by RefSeq, Jun 2012]
- ReactivityHuman, Mouse
- Storage Instruction-20°C or -80°C,2°C to 8°C
- UNSPSC12352203