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AK-1 [330461-64-8]

AK-1 [330461-64-8]

T5618
TargetMol Chemicals
CAS Number330461-64-8
Product group Chemicals
Estimated Purity99.01%
Molecular Weight403.45
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Overview

  • Supplier
    TargetMol Chemicals
  • Product Name
    AK-1 [330461-64-8]
  • Delivery Days Customer
    4
  • CAS Number
    330461-64-8
  • Certification
    Research Use Only
  • Chemical Name
    AK-1
  • Estimated Purity
    99.01%
  • Molecular Formula
    C19H21N3O5S
  • Molecular Weight
    403.45
  • Scientific Description
    AK-1 is a sirtuin 2 (SIRT2) inhibitor (IC50:12.5 microM).that prevents hippocampal neurodegeneration in Alzheimers disease models and induces cell cycle arrest in colon carcinoma cells.
  • Shelf life instruction
    3 years
  • SMILES
    [O-][N+](=O)c1cccc(NC(=O)c2cccc(c2)S(=O)(=O)N2CCCCCC2)c1
  • Storage Instruction
    -20°C
  • UNSPSC
    12352200

References

  • Outeiro TF, Kontopoulos E, Altmann SM, et al. Sirtuin 2 inhibitors rescue alpha-synuclein-mediated toxicity in models of Parkinson's disease. Science. 2007,317(5837):516-9.
    Read this paper