AKCI [669750-88-3]
HY-119948
CAS Number669750-88-3
Product group Chemicals
Molecular Weight369.46
Overview
- SupplierMedChem Express
- Product NameAKCI [669750-88-3]
- Delivery Days Customer9
- CAS Number669750-88-3
- CertificationResearch Use Only
- Molecular FormulaC19H27N7O
- Molecular Weight369.46
- Scientific DescriptionAKCI is a type of AURKC-IkappaBalpha interaction inhibitor, with an IC50 value of 24.9 microM. In MDA-MB-231 cells, AKCI can induce G2/M cell cycle arrest by regulating the p53/p21/CDC2/cyclin B1 pathway, inhibit cell migration and invasion, and reduce colony formation and tumor growth. AKCI can be used for research on breast cancer[1].
- SMILESCC1=CC=CC2=C(N=C(N=C12)NC3=NCN(CCN4CCOCC4)CN3)C
- UNSPSC12352200