AKI603 [1432515-73-5]

TargetMol Chemicals

AKI603 [1432515-73-5]

4

1432515-73-5

Chemical

Research Use Only

AKI603

99.81%

C19H23N9O2

409.45

AKI603 is a novel small molecule inhibitor of Aurora kinase A (AurA)(IC50 = 12.3 nM). AKI603 is developed to overcome resistance mediated by BCR-ABL-T315I mutation. AKI603 exhibits strong anti-proliferative activity in leukemic cells[1][2].

3 years

CN1CCN(CC1)c1cc(Nc2cc(C)[nH]n2)nc(Nc2ccc(cc2)[N+]([O-])=O)n1

-20°C

12352200