![ICC/IF analysis of COS7 cells transiently transfected with AKR1A1 plasmid using GTX84913 AKR1A1 antibody [6E3]. ICC/IF analysis of COS7 cells transiently transfected with AKR1A1 plasmid using GTX84913 AKR1A1 antibody [6E3].](https://www.genetex.com/upload/website/prouct_img/normal/GTX84913/GTX84913_1287_ICCIF_w_23061420_312.webp)
ICC/IF analysis of COS7 cells transiently transfected with AKR1A1 plasmid using GTX84913 AKR1A1 antibody [6E3].
AKR1A1 antibody [6E3]
GTX84913
ApplicationsFlow Cytometry, ImmunoFluorescence, Western Blot, ImmunoCytoChemistry, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
Product group Antibodies
ReactivityHuman
TargetAKR1A1
Overview
- SupplierGeneTex
- Product NameAKR1A1 antibody [6E3]
- Delivery Days Customer9
- Application Supplier NoteWB: 1:2000. ICC/IF: 1:100. IHC-P: 1:50. FACS: 1:100. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.
- ApplicationsFlow Cytometry, ImmunoFluorescence, Western Blot, ImmunoCytoChemistry, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
- CertificationResearch Use Only
- ClonalityMonoclonal
- Concentration0.74 mg/ml
- ConjugateUnconjugated
- Gene ID10327
- Target nameAKR1A1
- Target descriptionaldo-keto reductase family 1 member A1
- Target synonymsalcohol dehydrogenase; aldehyde reductase; aldo-keto reductase family 1 member A1; ALDR1; ALR; ARM; DD3; dihydrodiol dehydrogenase 3; epididymis secretory protein Li 6; epididymis secretory sperm binding protein Li 165mP; glucuronate reductase; glucuronolactone reductase; HEL-S-165mP; HEL-S-6
- HostMouse
- IsotypeIgG2a
- Protein IDP14550
- Protein NameAlcohol dehydrogenase [NADP(+)]
- Scientific DescriptionCatalyzes the NADPH-dependent reduction of a variety of aromatic and aliphatic aldehydes to their corresponding alcohols. Catalyzes the reduction of mevaldate to mevalonic acid and of glyceraldehyde to glycerol. Has broad substrate specificity. In vitro substrates include succinic semialdehyde, 4-nitrobenzaldehyde, 1,2-naphthoquinone, methylglyoxal, and D-glucuronic acid. Plays a role in the activation of procarcinogens, such as polycyclic aromatic hydrocarbon trans-dihydrodiols, and in the metabolism of various xenobiotics and drugs, including the anthracyclines doxorubicin (DOX) and daunorubicin (DAUN).
- ReactivityHuman
- Storage Instruction-20°C or -80°C,2°C to 8°C
- UNSPSC12352203
References
- Use of AKR1C1 and TKTL1 in the Diagnosis of Low-grade Squamous Intraepithelial Lesions from Mexican Women. Sequeda-Jurez A et al., 2020 Nov, Anticancer ResRead more