AKT-IN-24

MedChem Express

AKT-IN-24

5

Research Use Only

C32H28N2O10

600.57

KT-IN-24 (Compound M17) is a AKT allosteric inhibitor with anti-tumor activity. KT-IN-24 can target the AKT/mTOR and MEK/ERK signaling pathways and inhibit epithelial-mesenchymal transition, which has a synergistic suppressive effect on TNBC, promoting cell apoptosis while inhibiting proliferation and migration when used in combination with Trametinib (HY-10999)[1].

O=[N+](C1=C(C=CC=C1)OCC(NC2=CC=CC(CC(O[C@H](C/C=C(C)\C)C3=CC(C4=C(O)C=CC(O)=C4C3=O)=O)=O)=C2)=O)[O-]

12131703