AKT-IN-25

MedChem Express

AKT-IN-25

5

Research Use Only

C14H16N4O

256.30

AKT-IN-25 (Compound 14a) is an inhibitor for Akt, that inhibits the phosphorylation of Akt, and thereby inhibits the PI3K/Akt/mTOR signaling pathway. AKT-IN-25 arrests the cell cycle at G1 phase, inhibits the cell migration of PANC-1, and inhibits the proliferation of cancer cells PANC-1, PATU-T, and SUIT-2 with IC50s of 3.05, 1.32, and 3.85 microM, respectively[1].

O=C(N1C=C(N=N1)C2=CC=CC=C2)N3CCCCC3

12352200