AKT-IN-VIII [612847-09-3] [612847-09-3]
BS-6708C
CAS Number612847-09-3
Product group Chemicals
Estimated Purity98 - 98.0
Molecular Weight551.64
Overview
- SupplierBioss
- Product NameAKT-IN-VIII [612847-09-3] [612847-09-3]
- Delivery Days Customer16
- CAS Number612847-09-3
- CertificationResearch Use Only
- ConjugateUnconjugated
- Estimated Purity98 - 98.0
- Molecular FormulaC34 H29 N7 O
- Molecular Weight551.64
- Scientific DescriptionAKT-IN-VIII, also known as AKTi-1/2, is a potent, selective and ell permeable, allosteric inhibitor of Akt 1 and 2, which efficiently inhibits CaMKIalpha activity and aryl hydrocarbon receptor pathway. AKT-IN-VIII suppresses hyperthermia-induced Ndrg2 phosphorylation in gastric cancer cells. AKT-IN-VIII displays good selectivity against a panel of 70 other kinases with micromolar inhibition against some kinases, for example, calcium/calmodulin-dependent protein kinase 1 and smooth muscle myosin light-chain kinase.
- SMILESO=C1NC2C=CC=CC=2N1C1CCN(CC2C=CC(=CC=2)C2N=C3C=C4NC=NC4=CC3=NC=2C2C=CC=CC=2)CC1
- Storage Instruction-20°C
- UNSPSC12161509