AKT inhibitor VIII [612847-09-3]

MedChem Express

AKT inhibitor VIII [612847-09-3]

5

612847-09-3

Research Use Only

98.97

C34H29N7O

551.64

AKT inhibitor VIII (AKTi-1/2) is a cell-permeable quinoxaline compound that has been shown to potently, selectively, allosterically, and reversibly inhibit Akt1, Akt2, and Akt3 activity with IC50s of 58 nM, 210 nM, and 2119 nM, respectively.

O=C1NC2=CC=CC=C2N1C3CCN(CC4=CC=C(C5=NC6=CC(NC=N7)=C7C=C6N=C5C8=CC=CC=C8)C=C4)CC3

-20°C,2°C to 8°C

12352200