AL-8810

MedChem Express

AL-8810 [246246-19-5]

10

246246-19-5

99.00

C24H31FO4

402.50

AL-8810 is a potent and selective antagonist of the PGF 2alpha receptor (FP receptor). AL-8810 is an activator of MAPK and ERK1/2 . The K i of the FP receptor of mouse 3T3 cells and rat A7r5 cells are 0.2+/-0.06 microM and 0.4+/-0.1 microM, respectively. AL-8810 can be used in the study of elevated intraocular pressure (OHT) and primary open-angle glaucoma (POAG) [1] [2] [3] [4] [5] .

O=C(O)CCC/C=C\C[C@@H]1[C@@H](/C=C/[C@@H](C2CC3=C(C=CC=C3)C2)O)[C@@H](F)C[C@@H]1O

-20°C

12352200