alanyl-tRNA synthetase antibody [N1N2], N-term

GeneTex

alanyl-tRNA synthetase antibody [N1N2], N-term

9

WB: 1:500-1:3000. IHC-P: 1:100-1:1000. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.

Western Blot, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin

Research Use Only

Polyclonal

1 mg/ml

Unconjugated

AARS1

alanyl-tRNA synthetase 1

AARS; alanine tRNA ligase 1, cytoplasmic; alanine--tRNA ligase, cytoplasmic; alanyl-tRNA synthetase, cytoplasmic; alaRS; CMT2N; DEE29; EIEE29; renal carcinoma antigen NY-REN-42

Rabbit

IgG

Alanine--tRNA ligase, cytoplasmic

The human alanyl-tRNA synthetase (AARS) belongs to a family of tRNA synthases, of the class II enzymes. Class II tRNA synthases evolved early in evolution and are highly conserved. This is reflected by the fact that 498 of the 968-residue polypeptide human AARS shares 41% identity witht the E.coli protein. tRNA synthases are the enzymes that interpret the RNA code and attach specific aminoacids to the tRNAs that contain the cognate trinucleotide anticodons. They consist of a catalytic domain which interacts with the amino acid acceptor-T psi C helix of the tRNA, and a second domain which interacts with the rest of the tRNA structure. [provided by RefSeq]

Human

-20°C or -80°C,2°C to 8°C

12352203