Aldolase A antibody
GTX101408
ApplicationsWestern Blot, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
Product group Antibodies
ReactivityHuman, Mouse, Rat
TargetALDOA
Overview
- SupplierGeneTex
- Product NameAldolase A antibody
- Delivery Days Customer9
- Application Supplier NoteWB: 1:500-1:3000. IHC-P: 1:100-1:1000. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.
- ApplicationsWestern Blot, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
- CertificationResearch Use Only
- ClonalityPolyclonal
- Concentration0.58 mg/ml
- ConjugateUnconjugated
- Gene ID226
- Target nameALDOA
- Target descriptionaldolase, fructose-bisphosphate A
- Target synonymsALDA, GSD12, HEL-S-87p, fructose-bisphosphate aldolase A, aldolase A, fructose-bisphosphate, epididymis secretory sperm binding protein Li 87p, fructose-1,6-bisphosphate triosephosphate-lyase, lung cancer antigen NY-LU-1, muscle-type aldolase
- HostRabbit
- IsotypeIgG
- Protein IDP04075
- Protein NameFructose-bisphosphate aldolase A
- Scientific DescriptionThis gene encodes a member of the class I fructose-bisphosphate aldolase protein family. The encoded protein is a glycolytic enzyme that catalyzes the reversible conversion of fructose-1,6-bisphosphate to glyceraldehyde 3-phosphate and dihydroxyacetone phosphate. Three aldolase isozymes (A, B, and C), encoded by three different genes, are differentially expressed during development. Mutations in this gene have been associated with Glycogen Storage Disease XII, an autosomal recessive disorder associated with hemolytic anemia. Disruption of this gene also plays a role in the progression of multiple types of cancers. Related pseudogenes have been identified on chromosomes 3 and 10. [provided by RefSeq, Sep 2017]
- ReactivityHuman, Mouse, Rat
- Storage Instruction-20°C or -80°C,2°C to 8°C
- UNSPSC12352203
References
- Ruis K, Huynh O, Montales K, et al. Delineation of a minimal topoisomerase II binding protein 1 for regulated activation of ATR at DNA double-strand breaks. J Biol Chem. 2022,298(7):101992. doi: 10.1016/j.jbc.2022.101992Read this paper
- De Tomi E, Campagnari R, Orlandi E, et al. Upregulation of miR-34a-5p, miR-20a-3p and miR-29a-3p by Onconase in A375 Melanoma Cells Correlates with the Downregulation of Specific Onco-Proteins. Int J Mol Sci. 2022,23(3). doi: 10.3390/ijms23031647Read this paper
- Kim A, Montales K, Ruis K, et al. Biochemical analysis of TOPBP1 oligomerization. DNA Repair (Amst). 2020,96:102973. doi: 10.1016/j.dnarep.2020.102973Read this paper
- Chang SJ, Liao EC, Yeo HY, et al. Proteomic investigating the cooperative lethal effect of EGFR and MDM2 inhibitors on ovarian carcinoma. Arch Biochem Biophys. 2018,647:10-32. doi: 10.1016/j.abb.2018.04.004Read this paper
- Cardouat G, Duparc T, Fried S, et al. Ectopic adenine nucleotide translocase activity controls extracellular ADP levels and regulates the F(1)-ATPase-mediated HDL endocytosis pathway on hepatocytes. Biochim Biophys Acta Mol Cell Biol Lipids. 2017,1862(9):832-841. doi: 10.1016/j.bbalip.2017.05.005Read this paper




![FACS analysis of A549 cells using an isotype control (black) or Aldolase A antibody [AT3F9] at 2-5ug for 1,000,000 cells (red).](https://www.genetex.com/upload/website/prouct_img/normal/GTX16497/GTX16497_FACS_w_23060620_840.webp)

