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Aldose reductase-IN-3 [1390616-76-8]

HY-115977
MedChem Express
CAS Number1390616-76-8
Product group Chemicals
Molecular Weight401.89
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Overview

  • Supplier
    MedChem Express
  • Product Name
    Aldose reductase-IN-3 [1390616-76-8]
  • Delivery Days Customer
    10
  • CAS Number
    1390616-76-8
  • Certification
    Research Use Only
  • Molecular Formula
    C18H12ClN3O2S2
  • Molecular Weight
    401.89
  • Scientific Description
    Aldose reductase-IN-3 (Compound 5) is a potent and moderately selective inhibitor of aldose reductase (AR) with an IC50 of 3.99 microM. Aldose reductase has recently emerged as a molecular target that is involved in various inflammatory diseases, including sepsis. Aldose reductase-IN-3 has the potential for the research of sepsis[1].
  • SMILES
    O=C1N=C(NC2=NC3=CC=C(OC)C=C3S2)S/C1=C\C4=CC=C(Cl)C=C4
  • UNSPSC
    12352200