Aldumastat [1957278-93-1]

MedChem Express

Aldumastat [1957278-93-1]

10

1957278-93-1

Research Use Only

99.36

C20H24F2N4O3

406.43

Aldumastat (GLPG1972; S201086) is a potent, seletive and orally active ADAMTS-5 (IC50=19 nM) inhibitor, and has 8-fold seletivity over ADAMTS-4 (IC50=156 nM). Aldumastat has anticatabolic activity and is used for osteoarthritis research[1].

O=C(N(CCN1C2=CC(F)=CC(F)=C2)C[C@@H]1C)CC[C@](NC3=O)(C4CC4)C(N3)=O

-20°C,2°C to 8°C

12352200