Alemtuzumab

MedChem Express

Alemtuzumab [216503-57-0]

10

Research Use Only

Monoclonal

97.15

Alemtuzumab (Campath-IH) is a humanized monoclonal antibody against CD52 . Alemtuzumab does not cross-react with murine CD52. Alemtuzumab selectively targets the CD52 antigen to induce profound lymphocyte depletion, followed by recovery of T and B cells with regulatory phenotypes. Alemtuzumab is capable of complement-dependent cytotoxicity and antibody-dependent cell-mediated cytotoxicity (ADCC), as well as induction of apoptosis . Alemtuzumab has the potential for B-cell chronic lymphocytic leukaemia research [1] [2] .

-80°C

12352203