Bio-Connect

Alisertib (Standard) [1028486-01-2]

HY-10971R
MedChem Express
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Overview

  • Supplier
    MedChem Express
  • Product Name
    Alisertib (Standard) [1028486-01-2]
  • Delivery Days Customer
    999
  • Certification
    Research Use Only
  • Scientific Description
    Alisertib (Standard) is the analytical standard of Alisertib. This product is intended for research and analytical applications. Alisertib (MLN 8237) is an orally active and selective Aurora A kinase inhibitor (IC50=1.2 nM), which binds to Aurora A kinase resulting in mitotic spindle abnormalities, mitotic accumulation. Alisertib (MLN 8237) induces apoptosis and autophagy through targeting the AKT/mTOR/AMPK/p38 pathway in leukemic cells. Antitumor activity[1][2][3].
  • UNSPSC
    41116100