ALK2-IN-2 [2254409-25-9]

MedChem Express

ALK2-IN-2 [2254409-25-9]

10

2254409-25-9

Research Use Only

99.93

C28H27N5O2S

497.61

ALK2-IN-2 is an orally active and selective inhibitor of ALK2 (ACVR1), with an IC50 value of 9 nM, and over 700-fold selectivity against ALK3. ALK2-IN-2 can inhibit oxidative stress and protect endothelial cells[1][2].

CC(N1CCCC1)C(C=C2)=CC=C2C(C=N3)=CN4C3=C(C5=CC=C(S(=O)(N)=O)C6=C5C=CC=C6)C=N4

-20°C,2°C to 8°C

12352200