ALK5-IN-28 [2785430-84-2]

MedChem Express

ALK5-IN-28 [2785430-84-2]

10

2785430-84-2

Research Use Only

C25H27N7

425.53

ALK5-IN-28 (compound Ex-05) is a selective ALK-5 inhibitor (IC50≤10 nM), inhibits TGF-beta-induced SMAD signaling. ALK5-IN-28 has the potential to inhibit growth of tumour in vivo. ALK5-IN-28 can be used in study of proliferative diseases such as cancer, fibrotic diseases, and systemic sclerosis[1].

CC1=CC=CC2=C(NC3=NC(NC4=CC=C(CC5CCNCC5)C=C4)=NC=C3)C=NN=C12

12131703