ALKBH2 Polyclonal Antibody

Reddot Biotech

ALKBH2 Polyclonal Antibody

5

Western Blot, ELISA

Research Use Only

Polyclonal

0.3 mg/ml

Unconjugated

ALKBH2

alkB homolog 2, alpha-ketoglutarate dependent dioxygenase

2OG-Fe(II) oxy DC1; ABH2; alkB, alkylation repair homolog 2; alkylated DNA repair protein alkB homolog 2; alpha-ketoglutarate-dependent dioxygenase alkB homolog 2; DNA oxidative demethylase ALKBH2; oxy DC1

Rabbit

IgG

The Escherichia coli AlkB protein protects against the cytotoxicity of methylating agents by repair of the specific DNA lesions generated in single-stranded DNA. ALKBH2 and ALKBH3 are E. coli AlkB homologs that catalyze the removal of 1-methyladenine and 3-methylcytosine. Dioxygenase that repairs alkylated DNA and RNA containing 1-methyladenine and 3-methylcytosine by oxidative demethylation. Can also repair alkylated DNA containing 1-ethenoadenine (in vitro). Has strong preference for double-stranded DNA. Has low efficiency with single-stranded substrates. Requires molecular oxygen, alpha-ketoglutarate and iron.

Human, Mouse

-20°C

12352203