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ProductsBack/Alkyne-PEG4-maleimide [1262681-30-0]
Alkyne-PEG4-maleimide [1262681-30-0]

Alkyne-PEG4-maleimide [1262681-30-0]

Research Use Only
A270041
Antibodies.com
CAS Number1262681-30-0
Product group Chemicals
Estimated Purity95%
Molecular Weight311.33 kDa
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Overview

  • Supplier
    Antibodies.com
  • Product Name
    Alkyne-PEG4-maleimide [1262681-30-0]
  • Delivery Days Customer
    7
  • CAS Number
    1262681-30-0
  • Certification
    Research Use Only
  • Estimated Purity
    95%
  • Molecular Formula
    C15H21NO6
  • Molecular Weight
    311.33 kDa
  • Scientific Description
    When proteins or other sensitive biomolecules need to be conjugated, polyethyleneglycol (PEG) linkers are a great choice. They provide hydrophilicity and maintain separation between conjugated molecules. This linker based on PEG4, has a length of 14A (1.4 nm). Heterobifunctional linkers carrying different reactive groups can be used to prepare cross-conjugates between different molecules. The maleimide functional group is especially useful because they can label a site on a protein specifically. Most proteins have limited numbers of cysteine residues that selectively react with maleimides. Alkyne group can be then conjugated with azides in a selective copper-catalyzed process, CuAAc (copper-catalyzed alkyne azide cycloaddition).
  • UNSPSC
    41116134