Alkyne-PEG4-maleimide [1262681-30-0]

Antibodies.com

Alkyne-PEG4-maleimide [1262681-30-0]

7

1262681-30-0

Research Use Only

95% (by 1H NMR and HPLC-MS).

C15H21NO6

311.33 kDa

When proteins or other sensitive biomolecules need to be conjugated, polyethyleneglycol (PEG) linkers are a great choice. They provide hydrophilicity and maintain separation between conjugated molecules. This linker based on PEG4, has a length of 14A (1.4 nm). Heterobifunctional linkers carrying different reactive groups can be used to prepare cross-conjugates between different molecules. The maleimide functional group is especially useful because they can label a site on a protein specifically. Most proteins have limited numbers of cysteine residues that selectively react with maleimides. Alkyne group can be then conjugated with azides in a selective copper-catalyzed process, CuAAc (copper-catalyzed alkyne azide cycloaddition).

Shipped at room temperature. Upon delivery, store in the dark at -20°C. Avoid prolonged exposure to light. Desiccate.

12352200