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Alkyne Phosphoramidite, 5-terminal

Alkyne Phosphoramidite, 5-terminal

Research Use Only
A270042
Antibodies.com
Estimated Purity95%
Product group Chemicals
Molecular Weight409.50 kDa
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Overview

  • Supplier
    Antibodies.com
  • Product Name
    Alkyne Phosphoramidite, 5-terminal
  • Delivery Days Customer
    7
  • Certification
    Research Use Only
  • Estimated Purity
    95%
  • Molecular Formula
    C21H36N3O3P
  • Molecular Weight
    409.50 kDa
  • Scientific Description
    Phosphoramidite for the synthesis of oligonucleotides with 5-terminal alkyne for Click Chemistry. This alkyne amidite has several advantages over 5-hexynyl phosphoramidite, 5-butynyl-CEP, and other 5-terminal alkyne phosphoramidites. First, it is solid compound which is easier to handle and dispense. And due to its structure, it is also more stable in solution, and has a longer shelf life. The diluent for this phosphoramidite is acetonitrile. 5 min coupling time is recommended. Because this amidite does not contain 5-terminal DMT group, no 5-deprotection is needed. Oligonucleotides should be deblocked under standard conditions, and purified by PAGE, or ion exchange HPLC. Oligonucleotides with this modification are ideal for use in Click Chemistry.
  • UNSPSC
    41116134