Almonertinib (mesylate) [2134096-06-1]
HY-112823A
CAS Number2134096-06-1
Product group Chemicals
Estimated Purity99.67
Molecular Weight621.75
Overview
- SupplierMedChem Express
- Product NameAlmonertinib (mesylate) [2134096-06-1]
- Delivery Days Customer10
- CAS Number2134096-06-1
- CertificationResearch Use Only
- Estimated Purity99.67
- Molecular FormulaC31H39N7O5S
- Molecular Weight621.75
- Scientific DescriptionAlmonertinib (HS-10296) mesylate is an orally available, irreversible, third-generation EGFR tyrosine kinase inhibitor with high selectivity for EGFR-sensitizing and T790M resistance mutations. Almonertinib mesylate shows great inhibitory activity against T790M, T790M/L858R and T790M/Del19 (IC50: 0.37, 0.29 and 0.21 nM, respectively), and is less effective against wild type (3.39 nM). Almonertinib mesylate is used for the research of the non-small cell lung cancer[1][2].
- SMILESCOC(C=C(N(C)CCN(C)C)C(NC(C=C)=O)=C1)=C1NC2=NC(C3=CN(C4CC4)C5=C3C=CC=C5)=CC=N2.CS(=O)(O)=O
- Storage Instruction2°C to 8°C
- UNSPSC12352200