Bio-Connect

Alosetron [122852-42-0]

HY-70050A
MedChem Express
CAS Number122852-42-0
Product group Chemicals
Estimated Purity96.26
Molecular Weight294.35
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Overview

  • Supplier
    MedChem Express
  • Product Name
    Alosetron [122852-42-0]
  • Delivery Days Customer
    10
  • CAS Number
    122852-42-0
  • Certification
    Research Use Only
  • Estimated Purity
    96.26
  • Hazard Information
    h315, h319, h320
  • Molecular Formula
    C17H18N4O
  • Molecular Weight
    294.35
  • Scientific Description
    Alosetron (GR 68755) is a potent and highly selective serotonin 5-HT3 receptor antagonist. Alosetron is used for the research of irritable bowel syndrome (IBS). Alosetron blocks the fast 5HT3-mediated depolarisation of guinea-pig myenteric and submucosal neurons, with IC50 at ~55 nM. Alosetron attenuates the visceral nociceptive effect of rectal distension in conscious or anaesthetised dogs. Anti-inflammatory effects[1][2].
  • SMILES
    O=C(C(C1=C2C=CC=C1)=C(N2C)CC3)N3CC4=C(NC=N4)C
  • Storage Instruction
    -20°C,2°C to 8°C
  • UNSPSC
    12352200