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Alosetron (Hydrochloride)

HY-70050C
MedChem Express
CAS Number122852-69-1
DownloadMSDS
Product group Chemicals
Estimated Purity99.76
Molecular Weight330.81
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Overview

  • Supplier
    MedChem Express
  • Product Name
    Alosetron (Hydrochloride) [122852-69-1]
  • Delivery Days Customer
    5
  • CAS Number
    122852-69-1
  • Certification
    Research Use Only
  • Estimated Purity
    99.76
  • Molecular Formula
    C17H19ClN4O
  • Molecular Weight
    330.81
  • Scientific Description
    Alosetron Hydrochloride (GR 68755C) is a potent and highly selective serotonin 5-HT3 receptor antagonist. Alosetron Hydrochloride is used for the research of irritable bowel syndrome (IBS). Alosetron blocks the fast 5HT3-mediated depolarisation of guinea-pig myenteric and submucosal neurons, with IC 50 at ~55 nM. Alosetron Hydrochloride attenuates the visceral nociceptive effect of rectal distension in conscious or anaesthetised dogs. Anti-inflammatory effects [1] [2] .
  • SMILES
    O=C(C(C1=C2C=CC=C1)=C(N2C)CC3)N3CC4=C(NC=N4)C.[H]Cl
  • Storage Instruction
    2°C to 8°C
  • UNSPSC
    12352200