WB analysis of 1000ng, 500ng, 250ng and 125ng of a human alpha 2 Macroglobulin recombinant protein using GTX15643 alpha 2 Macroglobulin antibody [F1-P1C11 #3]. Dilution : 2 microg/ml
alpha 2 Macroglobulin antibody [F1-P1C11 #3]
GTX15643
ApplicationsImmunoPrecipitation, Western Blot, ELISA, RadioImmunoAssay
Product group Antibodies
ReactivityHuman
TargetA2M
Overview
- SupplierGeneTex
- Product Namealpha 2 Macroglobulin antibody [F1-P1C11 #3]
- Delivery Days Customer9
- Application Supplier NoteWB: 1-2 microg/ml. ELISA: 2 microg/ml. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.
- ApplicationsImmunoPrecipitation, Western Blot, ELISA, RadioImmunoAssay
- CertificationResearch Use Only
- ClonalityMonoclonal
- Clone IDF1-P1C11 #3
- Concentration1 mg/ml
- ConjugateUnconjugated
- FormulationLiquid
- Gene ID2
- Target nameA2M
- Target descriptionalpha-2-macroglobulin
- Target synonymsA2MD; alpha-2-M; alpha-2-macroglobulin; C3 and PZP-like alpha-2-macroglobulin domain-containing protein 5; CPAMD5; FWP007; S863-7
- HostMouse
- IsotypeIgG1
- Protein IDP01023
- Protein NameAlpha-2-macroglobulin
- Scientific DescriptionThe protein encoded by this gene is a protease inhibitor and cytokine transporter. It uses a bait-and-trap mechanism to inhibit a broad spectrum of proteases, including trypsin, thrombin and collagenase. It can also inhibit inflammatory cytokines, and it thus disrupts inflammatory cascades. Mutations in this gene are a cause of alpha-2-macroglobulin deficiency. This gene is implicated in Alzheimers disease (AD) due to its ability to mediate the clearance and degradation of A-beta, the major component of beta-amyloid deposits. A related pseudogene, which is also located on the p arm of chromosome 12, has been identified. [provided by RefSeq, Nov 2016]
- ReactivityHuman
- Storage Instruction-20°C or -80°C,2°C to 8°C
- UNSPSC12352203