alpha 2 Macroglobulin antibody [F1-P1C11 #3]

GeneTex

alpha 2 Macroglobulin antibody [F1-P1C11 #3]

9

WB: 1-2 microg/ml. ELISA: 2 microg/ml. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.

ImmunoPrecipitation, Western Blot, ELISA, RadioImmunoAssay

Research Use Only

Monoclonal

F1-P1C11 #3

1 mg/ml

Unconjugated

A2M

alpha-2-macroglobulin

A2MD, CPAMD5, FWP007, S863-7, alpha-2-macroglobulin, C3 and PZP-like alpha-2-macroglobulin domain-containing protein 5, alpha-2-M

Mouse

IgG1

Alpha-2-macroglobulin

The protein encoded by this gene is a protease inhibitor and cytokine transporter. It uses a bait-and-trap mechanism to inhibit a broad spectrum of proteases, including trypsin, thrombin and collagenase. It can also inhibit inflammatory cytokines, and it thus disrupts inflammatory cascades. Mutations in this gene are a cause of alpha-2-macroglobulin deficiency. This gene is implicated in Alzheimers disease (AD) due to its ability to mediate the clearance and degradation of A-beta, the major component of beta-amyloid deposits. A related pseudogene, which is also located on the p arm of chromosome 12, has been identified. [provided by RefSeq, Nov 2016]

Human

-20°C or -80°C,2°C to 8°C

12352203