
IHC-P analysis of formalin fixed human breast cancer tissue section using GTX54924 alpha 2c Adrenergic Receptor antibody. Antigen retrieval : Heat mediated antigen retrieval with sodium citrate buffer (pH 6.0)
alpha 2c Adrenergic Receptor antibody
GTX54924
ApplicationsWestern Blot, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
Product group Antibodies
ReactivityHuman, Mouse, Rat
TargetADRA2C
Overview
- SupplierGeneTex
- Product Namealpha 2c Adrenergic Receptor antibody
- Delivery Days Customer9
- Application Supplier NoteWB: 1:500 - 1:1000. IHC-P: 1:100 - 1:200. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.
- ApplicationsWestern Blot, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
- CertificationResearch Use Only
- ClonalityPolyclonal
- ConjugateUnconjugated
- Gene ID152
- Target nameADRA2C
- Target descriptionadrenoceptor alpha 2C
- Target synonymsADRA2L2; ADRA2RL2; ADRARL2; adrenergic, alpha-2C-, receptor; alpha-2 adrenergic receptor subtype C4; alpha2-AR-C4; alpha-2C adrenergic receptor; alpha-2C adrenoceptor; alpha-2C adrenoreceptor; ALPHA2CAR; alpha-2CAR
- HostRabbit
- IsotypeIgG
- Protein IDP18825
- Protein NameAlpha-2C adrenergic receptor
- Scientific DescriptionAlpha-2-adrenergic receptors are members of the G protein-coupled receptor superfamily. They include 3 highly homologous subtypes: alpha2A, alpha2B, and alpha2C. These receptors have a critical role in regulating neurotransmitter release from sympathetic nerves and from adrenergic neurons in the central nervous system. The mouse studies revealed that both the alpha2A and alpha2C subtypes were required for normal presynaptic control of transmitter release from sympathetic nerves in the heart and from central noradrenergic neurons. The alpha2A subtype inhibited transmitter release at high stimulation frequencies, whereas the alpha2C subtype modulated neurotransmission at lower levels of nerve activity. This gene encodes the alpha2C subtype, which contains no introns in either its coding or untranslated sequences. [provided by RefSeq, Jul 2008]
- ReactivityHuman, Mouse, Rat
- Storage Instruction-20°C or -80°C,2°C to 8°C
- UNSPSC12352203