alpha-Dendrotoxin

MedChem Express

alpha-Dendrotoxin [74504-53-3]

5

Research Use Only

alpha-Dendrotoxin (alpha-DTX) is a small molecule peptide neurotoxin isolated from the venom of the African green mamba snake (Dendroaspis angusticeps). alpha-Dendrotoxin is also a KV1.1, KV1.2, KV1.6 and ASIC channel blocker. alpha-Dendrotoxin blocks potassium channels, lowers the threshold of neuronal action potentials, and increases the frequency of action potentials, thereby enhancing neuronal excitability. alpha-Dendrotoxin can be used in neurotoxicology research[1].

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