WB analysis of HepG2 cell lysates using GTX23980 Alpha fetoprotein / AFP antibody [AFP-01]. Lane 1 : GTX23980 (reducing conditions) Lane 2 : GTX23980 (non-reducing conditions)
Alpha fetoprotein / AFP antibody [AFP-01]
GTX23980
ApplicationsImmunoPrecipitation, Western Blot, ELISA
Product group Antibodies
ReactivityHuman
TargetAFP
Overview
- SupplierGeneTex
- Product NameAlpha fetoprotein / AFP antibody [AFP-01]
- Delivery Days Customer9
- ApplicationsImmunoPrecipitation, Western Blot, ELISA
- CertificationResearch Use Only
- ClonalityMonoclonal
- Clone IDAFP-01
- ConjugateUnconjugated
- Gene ID174
- Target nameAFP
- Target descriptionalpha fetoprotein
- Target synonymsAFPD; alpha-1-fetoprotein; alpha-fetoglobulin; alpha-fetoprotein; FETA; HPAFP
- HostMouse
- IsotypeIgG1
- Scientific DescriptionThis gene encodes alpha-fetoprotein, a major plasma protein produced by the yolk sac and the liver during fetal life. Alpha-fetoprotein expression in adults is often associated with hepatoma or teratoma. However, hereditary persistance of alpha-fetoprotein may also be found in individuals with no obvious pathology. The protein is thought to be the fetal counterpart of serum albumin, and the alpha-fetoprotein and albumin genes are present in tandem in the same transcriptional orientation on chromosome 4. Alpha-fetoprotein is found in monomeric as well as dimeric and trimeric forms, and binds copper, nickel, fatty acids and bilirubin. The level of alpha-fetoprotein in amniotic fluid is used to measure renal loss of protein to screen for spina bifida and anencephaly. [provided by RefSeq, Jul 2008]
- ReactivityHuman
- Storage Instruction2°C to 8°C
- UNSPSC12352203
References
- Development and validation of an alpha fetoprotein immunoassay using Gyros technology. Given AM et al., 2012 May, J Pharm Biomed AnalRead more