alpha-GalCer analog 8 [922727-14-8]

TargetMol Chemicals

alpha-GalCer analog 8 [922727-14-8]

44

922727-14-8

Chemical

Research Use Only

alfa-GalCer analog 8

C50H97N3O8

868.339

alpha-Galactosylceramide analog 8 (alpha-GalCer analog 8) is a triazole derivative of alpha-galactosylceramide. [1] It increases IL-2 secretion by DN32.D3 NKT hybridoma cells when co-cultured with CD1d-transfected RBL cells pre-loaded with alpha-GalCer analog 8 at a concentration of 32 ng/ml. alpha-GalCer analog 8 (32 ng/ml) induces IL-4 secretion to a greater extent than the synthetic alpha-GalCer KRN 7000 in mouse splenocytes in vitro and in mouse serum following administration of a 1 &#181g per animal dose, indicating a Th2 response.

3 years

CCCCCCCCCCCCCCCCCCCCCCCCc1cn(nn1)[C@@H](CO[C@H]1O[C@H](CO)[C@H](O)[C@H](O)[C@H]1O)[C@H](O)[C@H](O)CCCCCCCCCCCCCC

-20°C

12352200