Alpha-Synuclein, Recombinant, Mouse

Cosmo Bio USA

Alpha-Synuclein, Recombinant, Mouse

16

Research Use Only

E. coli expressed mouse alpha-synuclein has been widely used in structural and functional studies. Masuda et. al. (1) have reported that approximately 20% of E. coli expressed mouse alpha-syn is mistranslated resulting in a Cys residue instead of Tyr at position 136 and causing an increase in the levels of dimeric alpha-synuclein. CSR-SYN04 is E. coli human alpha-Synuclein (human) expressed from a plasmid in which the TAC codon coding for Tyr136 in the mouse protein is replaced by TAT to produce protein expressing Tyr at position 136 homogenously. It can be used as mouse alpha-syn under similar conditions to that of in vivo. This product can also be used for comparison (control) of mouse alpha-Synuclein Fibrils (CSR-SYN05). Source: Mouse Expression system: E. coli Concentration: 1mg/mL Purity: ≥ 90% (SDS-Page) Storage: -20°C Related Products

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