alpha-Thujone [546-80-5]

MedChem Express

alpha-Thujone [546-80-5]

10

546-80-5

Research Use Only

98.07

C10H16O

152.237

alpha-Thujone is a monoterpene isolated from Thuja occidentalis essential oil with potent anti-tumor activities. alpha-Thujone is a reversible modulator of the GABA type A receptor and the IC50 for alpha-Thujone is 21 microM in suppressing the GABA-induced currents. alpha-Thujone induces ROS accumulation-dependent cytotoxicity, also induces cell apoptosis and autophagy. alpha-Thujone has antinociceptive, insecticidal, and anthelmintic activity, and can cross the blood-brain barrier[1][2][3].

O=C1C[C@]2(C(C)C)C[C@]2([H])[C@H]1C

-20°C,2°C to 8°C

12352200